Endocrine Abstracts

Background: Obesity associates with co-morbidities as non-alcoholic fatty liver disease (NAFLD). Obese men often present with low testosterone (T) levels. As sex steroids undergo hepatic metabolization and their serum levels depend on hepatic sex hormone binding globulin (SHBG) secretion, NAFLD could contribute to this phenomenon. Previous studies however were contradictory and not based on state-of-the-art technology as mass spectrometry or biopsy-proven NAFLD.<p class="a...

Background: Obesity induced inflammation is a key component in the pathogenesis of insulin resistance (IR). In addition, obesity-related non-alcoholic fatty liver disease (NAFLD) also seems to contribute to IR development. Until now, however, it is unclear which, if any component of NAFLD specifically associates with IR. Therefore, the aim is to assess if individual components of NAFLD contribute to IR in obese patients undergoing gastric bypass surgery (GBS).<p class="abs...

Background and aims: Obesity induced inflammation is a key component in the pathogenesis of insulin resistance (IR). In addition, obesity-related non-alcoholic fatty liver disease (NAFLD) also seems to contribute to IR development. Until now, however, it is unclear which, if any component of NAFLD specifically associates with IR. Therefore, the aim is to assess if individual components of NAFLD contribute to IR in obese patients undergoing gastric bypass surgery (GBS).<p c...